Flavones scaffold of Chromolaena odorata as a potential xanthine oxidase inhibitor: Induced Fit Docking and ADME studies
Introduction: Gout is a type of painful inflammation initiated by the interactions between monosodium urate crystals and connective tissue.Xanthine oxidase (XO) catalyzes the oxidation of hypoxanthine to xanthine, then to uric acid.The primary treatments for gout include XO inhibitors.At present, allopurinol is the most used XO inhibitor for the tr